Using hair dyes may soon be a thing of the past. Scientists have for the first time reversed premature greying of hair. British and German scientists have created a new compound that reverses oxidative stress, thus curing loss of hair or skin colour.
The researchers found that people who are going grey develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicles, which causes hair to bleach itself from the inside out.
The research now shows that this massive accumulation of hydrogen peroxide can be cured with a treatment developed by the researchers described as a topical UVBactivated compound called PC-KUS (a modified pseudocatalase).
The study also shows that the same treatment works for the skin condition vitiligo-a disease that causes skin depigmentation to almost 65 million people globally. Treatment options for vitiligo are presently limited.
Current options include phototherapy, which needs to be administered for three days every week for three years to achieve even partial pigmentation-that too in only 30% of the patients.
"To treat vitiligo, we analyzed an international group of 2,411 patients with vitiligo," said Karin Schallreuter, author of the study from the Institute for Pigmentary Disorders . Of that group, 57 or 2.4% were diagnosed with strictly segmental vitiligo (SSV), and 76 or 3.2% were diagnosed with mixed vitiligo.
Scientists found for the first time that patients who have SSV within a certain nerval distribution involving skin and eyelashes show the same oxidative stress as observed in the much more frequent general vitiligo.
The researchers found that people who are going grey develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicles, which causes hair to bleach itself from the inside out.
The research now shows that this massive accumulation of hydrogen peroxide can be cured with a treatment developed by the researchers described as a topical UVBactivated compound called PC-KUS (a modified pseudocatalase).
The study also shows that the same treatment works for the skin condition vitiligo-a disease that causes skin depigmentation to almost 65 million people globally. Treatment options for vitiligo are presently limited.
Current options include phototherapy, which needs to be administered for three days every week for three years to achieve even partial pigmentation-that too in only 30% of the patients.
"To treat vitiligo, we analyzed an international group of 2,411 patients with vitiligo," said Karin Schallreuter, author of the study from the Institute for Pigmentary Disorders . Of that group, 57 or 2.4% were diagnosed with strictly segmental vitiligo (SSV), and 76 or 3.2% were diagnosed with mixed vitiligo.
Scientists found for the first time that patients who have SSV within a certain nerval distribution involving skin and eyelashes show the same oxidative stress as observed in the much more frequent general vitiligo.
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